๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

A ternary complex of carbonic anhydrase: X-ray crystallographic structure of the adduct of human carbonic anhydrase II with the activator phenylalanine and the inhibitor azide

โœ Scribed by Fabrizio Briganti; Valeria Iaconi; Stefano Mangani; Pierluigi Orioli; Andrea Scozzafava; Guido Vernaglione; Claudiu T. Supuran


Book ID
108331665
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
746 KB
Volume
275-276
Category
Article
ISSN
0020-1693

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Crystallographic studies of inhibitor bi
โœ A. Elisabeth Eriksson; Per M. Kylsten; T. Alwyn Jones; Anders Liljas ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 961 KB

The binding of four inhibitors--mercuric ion, 3-acetoxymercuri-4-aminobenzenesulfonamide (AMS), acetazolamide (Diamox), and thiocyanate ion--to human carbonic anhydrase II (HCA II) has been studied with X-ray crystallography. The binding of mercury to HCA II at pH 7.0 has been investigated at 3.1 A

Carbonic anhydrase inhibitors. The X-ray
โœ Balendu Sankara Avvaru; Jason M. Wagner; Alfonso Maresca; Andrea Scozzafava; Art ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 916 KB

We investigated the inhibitory activity of several 1,3,4-thiadiazole-sulfonamides against all catalytically active CA (EC 4.2.1.1), CA I-XV. The tail derivatizing the 5-position in the 1,3,4-thiadiazole-2-sulfonamide scaffold was observed to be critical as an inhibitory determinant of these compound