## Abstract Viability, DNA synthesis and mitosis have been followed in the temperature sensitive Chinese hamster cell mutant K12 under permissive and non‐permissive conditions. On incubation at 40°C cells retained their ability to form colonies at 33°C for 15 to 20 hours, but viability was lost gra
A temperature-sensitive function in a Chinese hamster line affecting DNA synthesis
✍ Scribed by B. J. Smith; N. M. Wigglesworth
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- English
- Weight
- 644 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0021-9541
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✦ Synopsis
Abstract
A temperature‐sensitive (ts) mutant of Chinese hamster cells (K12) is blocked at a step late in G~1~, required for the initiation of DNA synthesis. The ts lesion is recessive in interspecific hybrids.
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