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A temperature-sensitive auxotropic variant of Chinese hamster ovary cells

✍ Scribed by C.H. Schröder; A.W. Hsie

Book ID
118876640
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
422 KB
Volume
91
Category
Article
ISSN
0014-4827

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## Abstract Variants of the Chinese hamster ovary cell line CHO‐K1 (ATCC CCL 61) which grow almost normally at 38.5°C but very poorly or not at all at 30°C were obtained after treatment with mutagens and application of an indirect selection procedure. Two kinds of variants were recovered. In the fi