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A Temperature-Guided Diastereoselectivity Switch During the Desymmetrization of meso-7-Azabicyclo[2.2.1]heptadiene: New Strategy towards the Synthesis of Aminocyclitols

โœ Scribed by Dr. Ganesh Pandey; Salla Rajender


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
408 KB
Volume
17
Category
Article
ISSN
0947-6539

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โœ M. L. TRUDELL; N. P. PAVRI ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 36 KB ๐Ÿ‘ 2 views

A New [4 + 2] Cycloaddition Strategy for the Synthesis of N-Acyl-7-azabicyclo[2.2.1]heptan-2-ones: A Formal Synthesis of (ยฑ)-Epibatidine. -The title compound (VIII), an intermediate for the preparation of (ยฑ)-epibatidine, is prepared via Diels-Alder reaction of allenes with N-acylated pyrrole (II)