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A TECHNIQUE FOR STEPWISE DEGRADATION OF PROTEINS FROM THE AMINO-END 1

โœ Scribed by Fraenkel-Conrat, H.

Book ID
126934219
Publisher
American Chemical Society
Year
1954
Tongue
English
Weight
284 KB
Volume
76
Category
Article
ISSN
0002-7863

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A method for selective isolation of the amino \(\mathrm{N}\)-terminal peptide from an \(\alpha\)-amino \(\left(N^{\alpha}\right.\) )-blocked protein is presented. The method consists of four steps. First, \(\epsilon-\) amino groups of lysine residues in the protein are succinylated. Second, the deri