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A technique for laser raman spectroscopic studies of isolated cell populations

โœ Scribed by Pierre Jeannesson; Michel Manfait; Jean-Claude Jardillier


Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
348 KB
Volume
129
Category
Article
ISSN
0003-2697

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โœฆ Synopsis


A new method has been developed for the study of cell populations by laser Raman spectroscopy. Resonance Raman spectra of a small number of living or fixed tumor cells (ca 5000) treated with the antitumor agent adriamycin have been successfully obtained. This new approach leads to a better understanding of the molecular interactions between drug and biological targets, i.e., nuclear DNA at the cellular level.


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