A technique for laser raman spectroscopic studies of isolated cell populations
โ Scribed by Pierre Jeannesson; Michel Manfait; Jean-Claude Jardillier
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 348 KB
- Volume
- 129
- Category
- Article
- ISSN
- 0003-2697
No coin nor oath required. For personal study only.
โฆ Synopsis
A new method has been developed for the study of cell populations by laser Raman spectroscopy. Resonance Raman spectra of a small number of living or fixed tumor cells (ca 5000) treated with the antitumor agent adriamycin have been successfully obtained. This new approach leads to a better understanding of the molecular interactions between drug and biological targets, i.e., nuclear DNA at the cellular level.
๐ SIMILAR VOLUMES
## Abstract Cell adhesion to material surfaces is one of the fundamental phenomena of cellular response to implanted devices. Controlling the strength, dynamics, and mechanics of cell adhesion offer opportunities for designing novel biomaterials for tissue engineering and biotechnology. Many techni
A thin-layer sample cell for examination of the spectra of hemoglobin at various degrees of gaseous-ligand saturation has been constructed to fit into a Cary 17 spectrophotometer. Small sample volumes of 50 ~1 are used. Equilibration times of only a few minutes are required between taking spectra at