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A systematic proteome-based approach for high-level extracellular production of recombinant proteins in Escherichia coli

✍ Scribed by Zhi-Gang Qian; Xiao-Xia Xia; Jong Hyun Choi; Sang Yup Lee

Book ID
118472803
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
71 KB
Volume
136
Category
Article
ISSN
0168-1656

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## Abstract Extracellular production of recombinant proteins in __Escherichia coli__ has several advantages over cytoplasmic or periplasmic production. However, nonpathogenic laboratory strains of __E. coli__ generally excrete only trace amounts of proteins into the culture medium under normal grow