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A Synthesis Strategy Yielding Skeletally Diverse Small Molecules Combinatorially

โœ Scribed by Burke, Martin D.; Berger, Eric M.; Schreiber, Stuart L.

Book ID
120516516
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
359 KB
Volume
126
Category
Article
ISSN
0002-7863

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Herein, we report a short and efficient synthetic pathway that uses intramolecular cyclization reactions of readily synthesized and densely functionalized amino alcohols. The research illustrates the implementation of a strategy that enables the synthesis, in only three to five steps, of a diverse c