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A Synthesis of Tamiflu by Using a Barium-Catalyzed Asymmetric Diels–Alder-Type Reaction

✍ Scribed by Kenzo Yamatsugu; Liang Yin; Shin Kamijo; Yasuaki Kimura; Motomu Kanai; Masakatsu Shibasaki


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
902 KB
Volume
48
Category
Article
ISSN
0044-8249

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Asymmetric diels alder reaction using py
✍ Choji Kashima; Yohei Miwa; Saori Shibata; Hiroyuki Nakazono 📂 Article 📅 2003 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 79 KB

## Abstract __N__‐Acylpyrazoles (**1**) were promising as good dienophiles, which were easily converted into the desired carboxylic derivatives. Bis(pyrazolyl)methanes, which were derived from chiral pyrazoles, showed the activity of chiral catalyst. Particularly 10 mol% of bis(isomenthopyrazol‐1,1