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A synthesis of pseudouridine

โœ Scribed by Brown, Daniel M.; Ogden, Richard C.


Book ID
121291045
Publisher
Royal Society of Chemistry
Year
1981
Weight
407 KB
Category
Article
ISSN
1472-7781

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๐Ÿ“œ SIMILAR VOLUMES


SYNTHESIS OF PSEUDOURIDINE
โœ Shapiro, Robert; Chambers, Robert Warner ๐Ÿ“‚ Article ๐Ÿ“… 1961 ๐Ÿ› American Chemical Society ๐ŸŒ English โš– 275 KB
A practical synthesis of the modified RN
โœ Patrick J. Grohar; Christine S. Chow ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 230 KB

An alternative synthesis of the modified RNA nucleoside pseudouridine is reported. This procedure employs coupling of an iodinated pyrimidine and a suitably protected lactone. The resulting hemiacetal is reduced and deprotected to yield pseudouridine.