1,2 Disubstituted methylenecyclopropyl bromides, 6 and 11, undergo radical cascade reactions, involving cyclisation, ring-opening and further cyclisation, to give cis bicyclic products in 67% and 41% yields respectively.
A synthesis of 4,6-dien-3-ones in the bicyclo[4.4.0]decane series
โ Scribed by A.J. Birch; K.P. Dastur
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- French
- Weight
- 93 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
The structures of a number of sesquiterpenes are based on the bicyclo[4.4.0]decane system, which in the past has frequently been elaborated by Robinson annelation.
๐ SIMILAR VOLUMES
We have reported the synthesis of bicyclo[4.2.0]octa-3,7-drene-2,5-dlone L1 which is the valence isomer of 2,4,7-cyclooctatriene-1,4-dione 2. 2 As to yet unknown 3,5,7-cyclooctatriene-1,2-drone 3, there can be two valence isomers, 4
diameter afforded two fractions with specific optical rotations [a]:& = +4.3 and -2.5 O . After a second passage the rotations were [a]:& = +7.5 ' and -5 '' (1 % in CHCI3).