## Abstract A heterotopic position of a limb allograft is advantageous in the fragile mouse model to reduce mortality but is prone to autotomy. The purpose of this study was to describe a new heterotopic limb transplantation model in the mouse for prolonged allograft survival. Eleven lower hindlimb
A subcutaneous mouse model for testing the virulence ofKlebsiellastrains
โ Scribed by A. M. Simoons-Smit; A. M. J. J. Verweij-Van Vught; I. Y. R. Kanis; D. M. MacLaren
- Publisher
- Springer Netherlands
- Year
- 1983
- Tongue
- English
- Weight
- 137 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0003-6072
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โฆ Synopsis
In our study of the role of K antigens in phagocytosis we compared six E. coli K ยง strains (K1, K2, K23, K(A)28, K(A)?, K(?) with their K-mutants. The induction of the chemiluminescence of PMN's after stimulation with K + and K-strains was enhanced for all K-strains. The kinetics of chemiluminescence production was dependent on the method of opsonization. The differences in opsono-phagocytosis between K ยง and K-strains as measured by chemiluminescence could mostly be explained by the ability of the K -strains to use the classical complement pathway for opsonization. The K antigens did not influence the function of common pili as far as the mannose-sensitive haemagglutination of guinea-pig erythrocytes is concerned.
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