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A study on diurnal mRNA expression of CYP1A1, AHR, ARNT, and PER2 in rat pituitary and liver

✍ Scribed by Ping Huang; Sandra Ceccatelli; Agneta Rannug

Book ID
117766109
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
147 KB
Volume
11
Category
Article
ISSN
1382-6689

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## Abstract We report a comprehensive examination of rat hepatic CYP1A2 and CYP2E1 ontogeny. We compare the data to human data to determine the rat's capacity as a model to identify CYP‐mediated mechanisms underlying age‐dependent differences in susceptibility to toxicity. We evaluated CYP expressi