A study of the interaction of electroconvulsive shock with chlorpromazine and reserpine in rats
β Scribed by C. B. Elam; E. C. Wortz; W. L. Brown
- Publisher
- Springer
- Year
- 1959
- Tongue
- English
- Weight
- 342 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0033-3158
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The chronic administration of ECS leads to a decrease of H3-1NE in all parts of the brain, and an increase in dihydroxymandelic acid, dihydroxy-13henylglykol, methoxy-hydroxymandelic acid, and methoxy-hydroxy13henylglykol. In the hy13othalamus and the cerebellum there is also an increase in normetan
Rats were trained to perform in discrimination learning reinforced by water for 6 days, and were intraperitoneally injected with chlorpromazine, reserpine, or d-amphetamine after each training session. Although chlorpromazineat the dose levels of 0.5 rag/ kg or more injected immediately after traini