A study of the inclusion complex of naproxen with β-cyclodextrin
✍ Scribed by ERDEN, N; CELEBI, N
- Book ID
- 120709846
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 467 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0378-5173
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📜 SIMILAR VOLUMES
The interaction of a nonsteroidal anti-inflammatory drug, naproxen, with \(\beta\)-CD has been studied by several analytical techniques, including 1-D and 2-D proton NMR, fluorescence spectroscopy, and FAB-MS. The negative ion FAB-MS confirmed the existence of a 1:1 inclusion complex of naproxen and
## Abstract An inclusion complex of fenbufen with β‐cyclodextrin (β‐CD) in aqueous solution was characterized by ^1^H‐NMR spectroscopy. The [1:1] stoichiometry was determined and a stability constant of several 1000s (__M__^−1^) was calculated. The geometry of the inclusion complex was established