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A Study of the [1,7]-Sigmatropic shift of a 1-hydroxylated-3-desoxy previtamin D to vitamin D: observation of a modest primary deuterium kinetic isotope effect

✍ Scribed by Okamura, William H.; Hoeger, Carl A.; Miller, Kelli J.; Reischl, Wolfgang.


Book ID
127143906
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
284 KB
Volume
110
Category
Article
ISSN
0002-7863

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Kinetics of thermal [1,7a]-sigmatropic s
✍ Jun-etsu Igarashi; Masahiko Ikeda; Makoto Sunagawa πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 244 KB

The quantitative evaluation of the [1,7a]-sigmatropic rearrangement of vitamin D 3 and its analogs affected by the conformations of the A ring using the 1H-NMR method was described. Although the side chain of the D ring had no effect on the hydrogen migration, the rearrangement was influenced by the