A Study Of Moisture Vapor Transmission Through Closures**College of Pharmacy, State University of Iowa, Iowa City
โ Scribed by Blaug, Seymour M. ;Hickman, Eugene ;Lach, John L.
- Publisher
- Elsevier
- Year
- 1958
- Weight
- 236 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0095-9553
No coin nor oath required. For personal study only.
โฆ Synopsis
Moisture vapor transmission through closures is an important consideration when
It is particularly important when packaging g ygroscopic materials or materials that decompose in the presence of trace amounts of moisture. The cap as well as the cap liner must be considered in choosing a proper closure. The barrier eficiency of sixteen liners in metal caps, phenolic, melamine, and mineral filled plastic caps was studied. Of the liners investigated, polyethylene, aluminum foil, plastic-wax saturated pulpboard, and red rubber liners were found to be the most effective moisture vapor barriers, particularly when used in metal closures.
ackaging pharmaceutical products.
HE SELECTION OF THE BEST possible closure for
Ta specific product is of great importance in the drug and chemical industry. Some of the factors to be considered are the type of product to be packaged, its hygroscopicity, and product reaction with the cap and/or the cap liner.
Although the liner may be effective and stable, the material of the cap may react with the product being packaged. This is particularly true of closures for liquid preparations.
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