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A Study of Genetic Markers in a Family with Polyendocrine Disease

✍ Scribed by M. J. Brueton; H. M. Chapel; L. P. Mackintosh


Book ID
115093131
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
117 KB
Volume
15
Category
Article
ISSN
0001-2815

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Studies of a DNA marker (G8) genetically
✍ Sandra Youngman; M. Sarfarazi; O. W. J. Quarrell; P. M. Conneally; Karen Gibbons πŸ“‚ Article πŸ“… 1986 πŸ› Springer 🌐 English βš– 493 KB

Close genetic linkage has been shown between the DNA sequence G8 (locus D4S10) and 16 British families with Huntington disease using the HindIII, EcoR1, Nci1, and Pst1 polymorphisms detected by G8, and by combining all the polymorphisms to give a combined haplotype. Two recombinants have been detect