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A Straightforward Synthesis of [3.3.0]Bicyclic Compounds

✍ Scribed by Lachaise, I.; Nohair, K.; Hakiki, M.; Nédélec, J. Y.


Book ID
117990866
Publisher
Taylor and Francis Group
Year
1995
Tongue
English
Weight
296 KB
Volume
25
Category
Article
ISSN
0039-7911

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The isoxazolidine derivative 6, prepared from an intermolecular 1,3dipolar cyeloaddition of the (5S)-unsaturated lactone 5 and N-methylnitrone, was effectively used for the synthesis of [3.3.0] bicyclic isoxazolidinyl cytidine 4a and thymidine 4b.