The reaction of (E)-1-alkenylboronic acids with (Z)-or(E)-1-alkenyl iodides in the presence of a catalytic amount of tetrakis(triphenylphosphine)palladium and sodium hydroxide gave the corresponding conjugated (E,E)-or (E,E)--alkadienes with high stereospecificity. Cross-coupling reactions between 1
A stereospecific synthesis of conjugated (E, Z)- and (Z, Z)-alikadienes by a palladium-catalyzed cross-coupling reaction of 1-alkenylboranes with 1-alkenyl bromides
โ Scribed by Norio Miyaura; Hiroshi Suginome; Akira Suzuki
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- French
- Weight
- 234 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
## Sumnary: The representative (E)-1-alkenyldisiamylboranes and (E)-1-alkenyl-1,3,2-benzodioxaboroles readily obtainable via hydroboration of 1-alkynes react with 1-alkenyl halides or l-alkynyl halides in the presence of a catalytic amount of tetrakis(triphenylphosphine)palladium and base to give
## STEREO-AND REGIOSPECIFIC SYNTHESES TO PROVIDE CONJUGATED (E,Zl -AND (Z,ZJ-ALKADIENES, AND ARYLATED (Z)-ALKENES IN EXCELLENT YIELDS VIA THE PALLADIUM-CATALYZED CROSS-COUPLING REACTIONS OF (Z)-l-ALKENYLBORONATES WITH l-BROMOALKENES AND ARYL IODIDES