𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A stereospecific synthesis of both enantiomers of 2-(1′-amino-2′-methylpropyl) imidazole, a key synthon in the synthesis of SB 203386; a potent protease inhibitor

✍ Scribed by Lendon N Pridgen; Mohamed K Mokhallalati; Michael A McGuire

Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
197 KB
Volume
38
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

ChemInform Abstract: A Stereospecific Sy
ChemInform Abstract: A Stereospecific Synthesis of Both Enantiomers of 2-(1′-Amino-2′- methylpropyl)imidazole, a Key Synthon in the Synthesis of SB 203386; a Potent Protease Inhibitor.
✍ L. N. PRIDGEN; M. K. MOKHALLALATI; M. A. MCGUIRE 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 2 views

A Stereospecific Synthesis of Both Enantiomers of 2-(1'-Amino-2'methylpropyl)imidazole, a Key Synthon in the Synthesis of SB 203386; a Potent Protease Inhibitor. -Two different diastereospecific approaches to chiral 2-(1-amino-2-methylpropyl)imidazoles (VI), parts of the inhibitor (VII), are develop

Enantioselective synthesis of both enant
Enantioselective synthesis of both enantiomers of 2-amino-2-(2-furyl)ethan-1-ol as a flexible building block for the preparation of serine and azasugars
✍ Ayhan S. Demir; Özge Sesenoglu; Hilal Aksoy-Cam; Handan Kaya; Kenan Aydogan 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 270 KB

The selective conversion of 1-(2-furyl)-2-hydroxyethan-1-one and ethyl 2-(2-furyl)-2-oxo acetate into (E)-and (Z)oximes and oxime ethers followed by oxazaborolidine-catalyzed enantioselective reduction using different amino alcohols furnished both enantiomers of the important chiral building block 2