ChemInform Abstract: A Practical Synthesis of (1S,2R)-1-Amino-2-indanol, a Key Component of an HIV Protease Inhibitor, Indinavir.
β Scribed by Hiroshi Kajiro; Shuichi Mitamura; Atsunori Mori; Tamejiro Hiyama
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 30 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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A Stereospecific Synthesis of Both Enantiomers of 2-(1'-Amino-2'methylpropyl)imidazole, a Key Synthon in the Synthesis of SB 203386; a Potent Protease Inhibitor. -Two different diastereospecific approaches to chiral 2-(1-amino-2-methylpropyl)imidazoles (VI), parts of the inhibitor (VII), are develop