## Since the discovery (2) of 'I-methoxy cephalosporins and their biological activity considerable attention has been directed towards the synthesis of a-methoxy-8-lactams (3). For some time we have been interested in the synthesis of B-alkoxy-8-lactams and have reported the preparation of one s
A stereoselective synthesis of α-alkoxy-β-lactams
✍ Scribed by Ajay K. Bose; B. Lal; B. Dayal; M.S. Manhas
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- French
- Weight
- 191 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
An efficient method for the preparation of chiral cis-3,4-disubstituted 8-1actams, based on reaction between imines from homochiral protected lactaldehydes and furfurylamine and phenyl dichlorophosphate activated carboxylic acid derivatives, is reported.
## Abstract The importance of the β‐lactam substructure is exemplified by the several classes of β‐lactam antibiotics. Among the synthetic routes available to obtain this interesting scaffold, the Kinugasa reaction is a convergent strategy. In this article, the synthesis of a variety of chiral β‐la
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