Efficient formal synthesis of (Β±)-axamid
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Kazunori Takahashi; Kentaro Takeda; Toshio Honda
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Article
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2010
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Elsevier Science
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French
β 492 KB
A formal synthesis of (Β±)-axamide-1 and (Β±)-axisonitrile-1 was achieved by using an intramolecular Hosomi-Sakurai reaction of the allylsilane derivative, as a key step, in which [(3-but-3-en-1-yl-3-methylcyclohex-1-en-1-yl)methyl](trimethyl)silane was transformed to a bicyclic compound possessing a