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A stereoselective synthesis of methyl β-C-lactoside through the tether approach

✍ Scribed by Gilles Rubinstenn; Jean-Maurice Mallet; Pierre Sinaÿ

Book ID
104259252
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
252 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis

Methyl ~-C-lactoside ([3-D-Galp-C-(l-->4)-~-Glcp-OMe) is stereoselectively synthesized by radical coupling of phenyl Se-[~ -D-galactopyranoside 5 onto exo-methylene-sugar 4, which are temporarily connected through a silaketal tether.

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