A stereoselective synthesis of 3-substituted hexahydroindeno[2,1-b]pyrroles via an intramolecular azomethine ylide cycloaddition
β Scribed by John D. Harling; Barry S. Orlek
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 422 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0040-4020
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β¦ Synopsis
3-Substituted hexahydroindeno[2,1-b]pyrroles were prepared in a stereoselective manner in high yield v/a an intramolecular azomethine ylide cycloaddition. Olefin geometry in the ylide precursor controlled the stereochemistry at the 3position.
π SIMILAR VOLUMES
## Abstract Regioβ and stereoselective syntheses of tetracyclic compounds having chromone, pyrrolidine, and piperidine rings have been accomplished by an intramolecular [3+2] cycloaddition reaction involving azomethine ylide. The reactions were carried out thermally as well as by irradiation with m
## Abstract The reaction of the compounds (I) with the compound (II) by heating in toluene gives the product (III) in similar yields but in longer reaction times (25β30 h).