Asymmetric, Stereocontrolled Total Synthesis of (+)- and (-)-Spirotryprostatin B via a Diastereoselective Azomethine Ylide [1,3]-Dipolar Cycloaddition Reaction.
โ Scribed by Paul R. Sebahar; Hiroyuki Osada; Takeo Usui; Robert M. Williams
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 26 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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## Dedicated to Professor Wei-Yuan Huang on the occasion of his 85th birthday The 1,3-dipolar cycloaddition of azomethine ylides to electron-deficient alkenes is one of the most powerful methods for the construction of highly substituted pyrrolidine rings. [1] Following early research on the prepa