A stereoselective route to 6-substituted pyrrolo-1,5-benzoxazepinones and their analogues
β Scribed by Brindisi, Margherita; Gemma, Sandra; Alfano, Gloria; Kshirsagar, Giridhar; Novellino, Ettore; Campiani, Giuseppe; Butini, Stefania
- Book ID
- 120834545
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- French
- Weight
- 739 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
Bis-tetrahydrofurans la and. l&, containing four chiral centers, are obtained with a 90 % iscmeric purity from gerzyl and neryl chlorides in four steps including tx~ stereoselective cyclizations.
6-Alkyl-and 6-(1-alkenyl)-5-iodo-2-pyrones, which are available as major products by reaction of the corresponding (Z)-2-en-4-ynoic acids with iodine and NaHCO 3 in CH 3 CN, undergo insertion of activated zinc metal into their carbon iodine bond to provide the corresponding 5-(iodozinc)-2-pyrones. H
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