A stereocontrolled route to the synthesis of (±)-3-amino-2,2-dimethyl-1,3-diphenylpropan-1-ol
✍ Scribed by M.N. Patil; K.C. Bhowmick; N.N. Joshi
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- French
- Weight
- 250 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
A novel asymmetric route to 2-amino-1,2,3,4-tetrahydronaphthalenes has been demonstrated starting from phthalimidovinylglycinol (PVG). Functionalisation of PVG via Heck reaction, olefin hydrogenation and cyclisation provides the title products.
Quarternary salts based upon 3-alkyl substituted 1-amino-1,2,3-triazolium cations (alkyl = methyl, ethyl, n-propyl, 2-propenyl, and n-butyl) have been synthesized and characterized by vibrational spectra, multinuclear NMR, elemental analysis, and DSC studies. Subsequent diazotization of these salts
## Abstract Acylation of 2,5‐dihydro‐2,2‐dimethyl‐1,3‐thiazoles leads to 3‐acyl‐2,3‐dihydro‐2,2‐dimethyl‐1,3‐thiazoles as potential starting materials for the total synthesis of racemic cephalosporins.