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A novel asymmetric route to 2-amino-1,2,3,4-tetrahydronaphthalenes

✍ Scribed by Michael C.J Harris; Mark Jackson; Ian C Lennon; James A Ramsden; Helen Samuel

Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
173 KB
Volume
41
Category
Article
ISSN
0040-4039

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✦ Synopsis

A novel asymmetric route to 2-amino-1,2,3,4-tetrahydronaphthalenes has been demonstrated starting from phthalimidovinylglycinol (PVG). Functionalisation of PVG via Heck reaction, olefin hydrogenation and cyclisation provides the title products.

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