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A statistical test of hypotheses on the organization and origin of the genetic code

✍ Scribed by Eörs Szathmáry; Elias Zintzaras

Publisher
Springer
Year
1992
Tongue
English
Weight
375 KB
Volume
35
Category
Article
ISSN
0022-2844

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✦ Synopsis

Theories of the origin of the genetic code assign different weights to amino acid propel-ties such as polarity and precursor-product relationship. Previous statistical work on the origin of the genetic code has produced controversial results. We analyze relationships between various amino acid and tRNA properties by one and the same statistical method. It is shown that polarities as well as precursor-product relationships are both likely to have been important in shaping the genetic code, together with codon swapping that left protein sequences intact.

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