The main theories which have been suggested to explain the origin of genetic code organization are discussed. The coevolution theory, which considers the genetic code as a map of the biosynthetic relationships between amino acids, seems to be based on a mechanism that links it closely to certain sta
A speculation on the origin of the genetic code
β Scribed by D.C. Reanney; R.K. Ralph
- Publisher
- Elsevier Science
- Year
- 1967
- Tongue
- English
- Weight
- 824 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0022-5193
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The origin of the organisation of the genetic code reflects both the biosynthetic relationships between amino acids and the physicochemical interactions between these and anticodons; moreover, these two forces do not act independently. It must therefore be explained why it is simultaneously true tha
We argue that a primitive genetic code with only 20 separate words explains that there are 20 coded amino acids in modern life. The existence of 64 words on the modern genetic code requires modern life to read almost exclusively one strand of DNA in one direction. In our primitive code, both the ori
RNAs that catalyse their own aminoacylation have been recently selected in vitro. These findings support the notion that the primitive aminoacyl-tRNA synthetases may have been RNAs. In this paper, we propose a structural model for the first aminoacyl-tRNA synthetase consisting of an RNA complex form
## Abstract The genetic code is nearly universal, and the arrangement of the codons in the standard codon table is highly nonrandom. The three main concepts on the origin and evolution of the code are the stereochemical theory, according to which codon assignments are dictated by physicochemical af