A graph theoretical approach to the effe
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Shah Md. Abdur Rauf; Mohamed Ismael; Kamlesh Kumar Sahu; Ai Suzuki; Riadh Sahnou
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Article
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2009
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Versita
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English
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## Abstract Tumor suppressor protein p53 becomes inactive due to mutation on its DNA binding core domain leading to misbehavior of this protein and preventing its interaction with DNA. In the present study, changes of the protein conformation by five hot spot mutations of T-p53C were assessed preve