๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

A spleen weight assay for murine sarcoma virus harvey (MSV-H)

โœ Scribed by Martin S. Hirsch; Jennifer J. Harvey

Publisher
John Wiley and Sons
Year
1969
Tongue
French
Weight
380 KB
Volume
4
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

โœฆ Synopsis

A spleen weight assay has been developed for tifrating murine sarcoma virus-Harvey ( M S V -H ) 3 weeks after intraperitoneal infection of newborn BALBIc and random-bred albino mice. Induction of splenomegaly corresponded in time with divelopment of sarcomas and anaemia. The assay was also used to evaluate sera for neutralizing antibodies to MS V-H. Weanling mice were much less susceptible to erythroblastic splenomegaly and tumour induction than newborns. Random-bred mice were ,found more satisfactory for the assays than BALB/c mice. Newborn Sprague-Dawley rats also responded to MS V-H inoculation with a dose-dependent erythroblastic splenomegaly.

๐Ÿ“œ SIMILAR VOLUMES

Biological activity and separation of a
Biological activity and separation of a leukaemogenic virus from murine sarcoma virus-harvey (MSV-H)
โœ Jennifer J. Harvey; June East ๐Ÿ“‚ Article ๐Ÿ“… 1969 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 785 KB

Twelve diflerent preparations of Murine Sarcoma Virus-Harvey ( M S V -H ) had leukaemogenic activity when tested in BALBIc and C,H/Bi mice or Sprague-Dawley rats, some of which ultimately developed generalized lymphocytic leukaemia instead of reacting rapidly and characteristically with sarcoma form