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A solvent-free protocol for one pot conversion of Baylis Hillman acetates to pyridopyrimidinones

✍ Scribed by R. Sreevani; A. Manjula; B. Vittal Rao

Book ID: 102343186
Publisher: Journal of Heterocyclic Chemistry
Year: 2011
Tongue: English
Weight: 134 KB
Volume: 48
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.560

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✦ Synopsis

Abstract

A facile one pot transformation of Baylis Hillman acetates to pyrido[1,2‐a]pyrimidin‐2‐ones by reaction with 2‐amino pyridine in a total solvent‐free protocol is illustrated. The 3‐substituted‐2H‐pyrido[1,2‐a]pyrimidin‐2‐ones are obtained in pure form without involving any purification technique or solvent. J. Heterocyclic Chem., (2011).

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