A Facile One-Pot Conversion of Acetates of the Baylis−Hillman Adducts to [ E ]-α-Methylcinnamic Acids
✍ Scribed by Basavaiah, Deevi; Krishnamacharyulu, Marimganti; Hyma, Rachakonda Suguna; Sarma, Pakala K. S.; Kumaragurubaran, Nagaswamy
- Book ID
- 121356109
- Publisher
- American Chemical Society
- Year
- 1999
- Tongue
- English
- Weight
- 165 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0022-3263
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📜 SIMILAR VOLUMES
A facile, one-pot convenient transformation of the acetates of Baylis-Hillman adducts into fused pyrimidones, i.e. 3-substituted-1,5-diazabicyclo(4.4.0)deca-2,5,7,9-tetraen-4-ones via reaction with 2-aminopyridine in environmentally friendly aqueous media is described.
## Abstract A facile one pot transformation of Baylis Hillman acetates to pyrido[1,2‐a]pyrimidin‐2‐ones by reaction with 2‐amino pyridine in a total solvent‐free protocol is illustrated. The 3‐substituted‐2H‐pyrido[1,2‐a]pyrimidin‐2‐ones are obtained in pure form without involving any purification
A facile route for the synthesis of novel 3,5,6-trisubstituted-2-pyridones from the acetylated Baylis-Hillman esters with b-enamino esters or b-enamino nitriles in one pot with good yields is described.