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A solution-phase parallel synthesis of alkylated guanidines from thioisocyanates and amines

โœ Scribed by Bogolubsky, Andrey V.; Grishchenko, Alexander; Pipko, Sergey E.; Konovets, Anzhelika; Chuprina, Alexander; Tolmachev, Andrey; Boyko, Alexander N.; Chekotylo, Alexey; Lukin, Oleg

Book ID
120265703
Publisher
Springer
Year
2013
Tongue
English
Weight
340 KB
Volume
17
Category
Article
ISSN
1381-1991

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A new reagent for solid and solution pha
A new reagent for solid and solution phase synthesis of protected guanidines from amines
โœ Yaw Fui Yong; Jennifer A. Kowalski; Jason C. Thoen; Mark A. Lipton ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 217 KB

A new reagent --4-nitro-l-H-pyrazole-l-[N, N'-bis(ten-butoxycarbonyl)]cmboxamidine --has been develolxd to effect the rapid a~l efficient synthesis of I~(~)-pmtected guanidin~ from and secendm3, amines. The reagent is a more eleclrophilic, sad comfy more derivative of the literature reagent l-H-pyra