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A soluble interleukin-6 receptor mutant inhibits interleukin-6-induced signal transduction in myeloma cells

✍ Scribed by Lun Song; Beifen Shen; Yunfang Ren


Book ID
110346388
Publisher
Springer Netherlands
Year
2002
Tongue
English
Weight
110 KB
Volume
24
Category
Article
ISSN
0141-5492

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This paper reports on cDNA coding for the SO-kDa murine IL6 receptor (mlL6R) that was cloned from a mouse liver cDNA library. Human hepatoma Hep3B cells transfected transiently or stably with an expression vector carrying the entire coding region for mIL6R become responsive to mouse IL6 (mIL 6).We m