𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A Soluble Base for the Copper-Catalyzed Imidazole N-Arylations with Aryl Halides†

✍ Scribed by Liu, Longbin; Frohn, Mike; Xi, Ning; Dominguez, Celia; Hungate, Randy; Reider, Paul J.

Book ID
115531703
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
116 KB
Volume
70
Category
Article
ISSN
0022-3263

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Copper-catalyzed N-Arylation of Imidazol
Copper-catalyzed N-Arylation of Imidazoles with Aryl or Heteroaryl Halides Facilitated by Dimethylglyoxime in Water
✍ Xiangmei Wu; Weiya Hu 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 231 KB 👁 1 views

## Abstract A combination of CuSO~4~/dimethylglyoxime was found to be an efficient and inexpensive catalyst system for __N__‐arylation of imidazole and benzimidazole with aryl halides and heteroaryl halides in water, providing the corresponding products in moderate to good yields.

An efficient copper-catalyzed coupling o
An efficient copper-catalyzed coupling of aryl halides with imidazoles
✍ Ayumu Kiyomori; Jean-François Marcoux; Stephen L. Buchwald 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 230 KB

Copper-catalyzed N-arylation of imidazoles can be accomplished using (CuOTf)2°benzene as a copper source and Cs2CO3 as a base in xylenes at 110-125 °C. Addition of 1,10-phenanthroline (phen) and trans, trans-dibenzylideneacetone (dba) was crucial to the success of the process. The products, N-arylim