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A single nucleotide polymorphism in the E-cadherin gene promoter modifies the risk of prostate cancer

✍ Scribed by Bas Verhage; Kjeld van Houwelingen; Emiel Ruijter; Bart Kiemeney; Jack Schalken


Book ID
118643396
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
177 KB
Volume
1
Category
Article
ISSN
1569-9056

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## Abstract The __E‐cadherin__ (__CDH1__) gene has been associated with prostate carcinogenesis. The C/A polymorphism βˆ’160 base pairs relative to the transcription start site has been shown to decrease gene transcription. We analyzed the association between this polymorphism and the risk of sporadi