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A Single Nucleotide Polymorphism in the Carboxylesterase Gene Is Associated with the Responsiveness to Imidapril Medication and the Promoter Activity

✍ Scribed by GESHI, Eiichi; KIMURA, Tomomi; YOSHIMURA, Mika; SUZUKI, Hiroshi; KOBA, Shinji; SAKAI, Tetsuo; SAITO, Tsukasa; KOGA, Atsuro; MURAMATSU, Masaaki; KATAGIRI, Takashi

Book ID: 119987453
Publisher: Nature Publishing Group
Year: 2005
Tongue: English
Weight: 204 KB
Volume: 28
Category: Article
ISSN: 0916-9636
DOI: 10.1291/hypres.28.719

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## Abstract Matrix metalloproteinase (MMP)‐1 is associated with tumor cell invasion and metastasis, and its promoter polymorphism has been shown to influence the transcriptional level. Our study explored the association between this polymorphism and renal cell carcinoma in a Japanese population. DN