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A simplified preparation of activated magnesium for grignard reagents

✍ Scribed by Henry Gilman; Robert H. Kirby


Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
417 KB
Volume
54
Category
Article
ISSN
0165-0513

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πŸ“œ SIMILAR VOLUMES


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Using a simple apparatus addltlon of 2-alkenyl halldes to precondensed active Mg In THF gave clean solutions of 2-alkenylmagneslum halldes which on carbonation furnished 8,y-unsaturated carboxyllc acids In high yields.

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3-,4-Pyridyl and 4-quinolyl Grignard reagents were generated by the reaction of the corresponding phenyl sulfoxides with PhMgBr and give the adducts upon treatment with various aldehydes and ketones. The stereochemistry for the reaction