Thioglycidyl esters of monobasic carboxylic acids were synthesized by thioepoxidation of glycidyl esters of thiourea. Despite the fact that data on the methods of synthesis and on the properties of thiirane compounds have been correlated and systematized in a monograph [i], the amount of data in th
A simple synthesis of some hydroxypyridine carboxylic acids
β Scribed by F. W. Broekman; A. van Veldhuizen; H. Janssen
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 272 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0165-0513
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β¦ Synopsis
Abstract
A simple method for the synthesis of 3βhydroxypicolinic acid and 4βhydroxynicotinic acid via the cyano compounds starting from 3βhydroxyβ2βiodoβ or 4βhydroxyβ3βiodopyridine, is described.
π SIMILAR VOLUMES
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Four organic salt complexes of 3-hydroxypyridine (3-HP) with nitro-substituted aromatic and heterocyclic carboxylic acids have been prepared and their X-ray crystal structures reported. These complexes are 3-hydroxypyridinium 5-nitrofuran-2-carboxylate 1, 3-hydroxypyridinium 4-nitrobenzoate 2, 3-hyd
by basic hydrolysis is the standard method to prepare cyclopropene carboxylic acidst2). We have found, however, that if the cyclopropene resulting from the initial addition has a benzylic hydrogen adjacent to the ring, the alkaline hydrolysis condition lead instead to methylenecyclopropane acids. T