## Abstract Tourette syndrome (TS) is a neuropsychiatric disorder characterized by multiple motor and phonic tics. The heritability of TS has been well established, yet there is a lack of consensus in genomeβwide linkage studies. The purpose of this study was to conduct a genomeβwide linkage analys
A simple scheme for the analysis of HLA linkages in pedigrees
β Scribed by JURG OTT
- Book ID
- 115248647
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 193 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0003-4800
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The affected-pedigree-member (APM) method is a non-parametric method of linkage analysis, which requires no assumptions about how the trait of interest is inherited [Weeks and Lange, 1988, 1991, 1992; Lange and Weeks, 1990; Weeks et al., 1992]. The APM method uses only the affected members of each p
Three hundred four HLA-A : HLA-B : Bf haplotypes of the Japanese population as deduced by family analysis are described. Several linkage disequilibriums were observed in the following two-factor haplotypes: HLA-A and HLA-B, HLA-A and Bf, and HLA-B and Bf. Positive linkage disequilibriums between HLA