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A simple preparation of N-protected chiral α-aminonitriles from N-protected α-amino acid amides

✍ Scribed by Philippe Maetz; Marc Rodriguez

Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
109 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis

N-protected cX-amino-acid amides are dehydrated to N-protected ~-aminonitriles in good yields and with excellent purities by reaction of the corresponding primary amides with cyanuric chloride in DMF.

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