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A Simple, Modular Synthesis of Substituted Pyridines

โœ Scribed by Liu, Songbai; Liebeskind, Lanny S.


Book ID
111980129
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
94 KB
Volume
130
Category
Article
ISSN
0002-7863

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## Abstract A particularly straightforward and efficient protocol for the synthesis of highly substituted pyridines, based on a condensation reaction of ฮฒโ€aminocrotonitrile and easily accessible (__E__)โ€2โ€oxoโ€4โ€arylโ€butโ€3โ€enoic acids and (__E__)โ€4โ€oxoโ€4โ€arylโ€butโ€2โ€enoic acids is described. J. Heter