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A simple, diversity oriented synthesis of highly substituted pyridines

✍ Scribed by Katarzyna Kaczanowska; Holger Eickhoff; Klaus Albert; Karl-Heinz Wiesmüller; Arnaud-Pierre Schaffner

Book ID
102343244
Publisher
Journal of Heterocyclic Chemistry
Year
2011
Tongue
English
Weight
143 KB
Volume
48
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

A particularly straightforward and efficient protocol for the synthesis of highly substituted pyridines, based on a condensation reaction of β‐aminocrotonitrile and easily accessible (E)‐2‐oxo‐4‐aryl‐but‐3‐enoic acids and (E)‐4‐oxo‐4‐aryl‐but‐2‐enoic acids is described. J. Heterocyclic Chem., (2011).

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