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A simple, mild, and efficient procedure for high-yield synthesis of benzimidazoles using coppertriflate as catalyst

✍ Scribed by M. Adharvana Chari; P. Sadanandam; D. Shobha; K. Mukkanti

Publisher: Journal of Heterocyclic Chemistry
Year: 2010
Tongue: English
Weight: 123 KB
Volume: 47
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.287

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✦ Synopsis

Abstract

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Copper triflate has been found to be an efficient catalyst for the synthesis of benzimidazoles from o‐phenylenediamine and aldehydes at reflux temperature under acetonitrile solvent. This new method consistently has the advantage of excellent yields (74–95%) at reflux temperature. J. Heterocyclic Chem., 2010.

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