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A simple method of β-aminophosphonates synthesis

✍ Scribed by E. V. Grishkun; O. I. Kolodyazhnyi


Book ID
111757854
Publisher
Springer
Year
2009
Tongue
English
Weight
131 KB
Volume
79
Category
Article
ISSN
1070-3632

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📜 SIMILAR VOLUMES


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Vinylogous iminium salts from g-aminoenamines react with triethylphosphite to aord amino phosphonates in moderate to good yields. The latter are easily converted to a-substituted aminoallylphosphonates that can yield a-substituted aminoallylphosphonates on reaction with butyllitium and a series of e

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The gold(I) catalyzed aldol reaction of diethyl a-isocyanomethylphosphonate with benzaldeyde gave the oxazoline 3, a P-hydroxy-a-aminophosphonic acid precursor, with high enantioand diastereoselectivity (98 % tram, 85 % ee) by employing a chiral ferrocenylamine ligand. The use of 31P NMR spectroscop