✦ LIBER ✦

A simple method of testing sensitivity of human tumors to antitumor agents in vivo

✍ Scribed by A. Lockshin; N. I. Polyanskaya; Yu. V. Mashkovtsev; K. G. Dzyubanov

Publisher: Springer US
Year: 1991
Tongue: English
Weight: 305 KB
Volume: 112
Category: Article
ISSN: 0007-4888
DOI: 10.1007/bf00841384

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Differential sensitivity of various huma

Differential sensitivity of various human tumors to inhibition of poly amine biosynthesis in vivo

✍ Rami Saydjari; Robert W. Alexander; JR. James R. Upp; Sam C. Barranco; JR. Court 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 485 KB

Polyamines are essential for normal and neoplastic growth. Ornithine decarboxylase (ODC) is the first and rate-limiting enzyme in the polyamine biosynthetic pathway. a-Difluoromethylornithine (DFMO) is an enzyme-activated irreversible inhibitor of ODC, and a known anti-neoplastic agent. The purpose

Properties of anticancer agents relevant

Properties of anticancer agents relevant to in vitro determinations of human tumor cell sensitivity

✍ Edward J. Pavlik; Daniel E. Kenady; John R. Nagell; Kathryn Keaton; Michael B. H 📂 Article 📅 1983 🏛 Springer 🌐 English ⚖ 627 KB

Human colorectal carcinoma: Patterns of

Human colorectal carcinoma: Patterns of sensitivity to chemotherapeutic agents in the human tumor stem cell assay

✍ Michael V. Agrez; John S. Kovach; Robert W. Beart Jr.; Joseph Rubin; Charles G. 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 English ⚖ 436 KB 👁 1 views

Xenografts in pharmacologically immunosu

Xenografts in pharmacologically immunosuppressed mice as a model to test the chemotherapeutic sensitivity of human tumors

✍ G. L. Floersheim; A. Bieri; Nicole Chiodetti 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 French ⚖ 577 KB

A human tumor xenograft model using pharmacologically immunosuppressed mice was assessed for its suitability to test preclinically the sensitivity of colorectal carcinomas, bone sarcomas and melanomas against anticancer agents. Besides ionizing radiation, 14 cytotoxic drugs including 5-fluorouracil

Differential in vitro sensitivity of hum

Differential in vitro sensitivity of human tumor and normal cells to chemotherapeutic agents and resistance modulators

✍ Peter Nygren; Rolf Larsson 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 793 KB

DIFFERENTIAL CYTOTOXIC SENSITIVITY OF HUMAN NORMAL AND TUMOR CELLS 599 TABLE I -CHARACTERISTICS OF THE INVESTIGATED HUMAN CELL TYPES' ~ Cell type Origin Characteristic Type of culture Growth rate in vifro exDreSS,On Pgp, ACHN LO Lloo Fibroblasts Lymphocytes CLL, AML Cells from solid tnmors Kidney ad

In vitro sensitivity testing of human re

In vitro sensitivity testing of human renal cell carcinoma with cytostatic agents and interferon alpha-2a

✍ de Riese, W. ;Allhoff, E. ;Stief, C. G. ;Lenis, G. ;Schlick, R. ;Liedke, S. ;Ant 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 602 KB

Samples of 38 human renal cell carcinomas (RCC) were subjected to routine histopathological examination but also to in vitro sensitivity testing with mitomycin C, vinblastine and interferon Alpha-2a at various concentrations corresponding to serum titers recommended to be effective in vivo, employin